GHK-Cu (often called copper peptide) is a naturally occurring tripeptide made of three amino acidsâGlycine-Histidine-Lysine (GHK)âbound to a copper ion (Cu²âş).
Itâs best known for its roles in skin repair, anti-aging, and hair health, and itâs widely used in dermatology and cosmetic science. GHK-Cu is found naturally in human plasma, saliva, and urine. Its levels decline with age.
Key biological actions
- Stimulates collagen, elastin, and proteoglycan production
- Promotes wound healing and tissue repair
- Reduces inflammation
- Improves skin barrier function
- Supports antioxidant activity
- Signals gene expression linked to regeneration
Skin and cosmetic benefits
- Reducing fine lines and wrinkles
- Improving skin firmness and elasticity
- Enhancing skin texture and tone
- Speeding up post-procedure healing (e.g., after micro needling or laser)
- Reducing hyperpigmentation
Hair and scalp benefits
- Support hair follicle health
- Increase hair thickness
- Reduce hair shedding
- Improve scalp condition
Medical and research uses
- Wound care
- Nerve regeneration
- Anti-inflammatory therapies
- Potential anti-fibrotic effects
Safety and side effects
- Generally considered safe and well-tolerated in topical use
- Rarely causes irritation
- Injectable or systemic use should only be under medical supervision
 Disclaimer: This is for research and informational purposes only. For medical advice or diagnosis, consult a professional.
